Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102138 | 1.00 | KIF11 (0.43) | KIF11HTTNR4A1NR4A2NR4A3 | |
| SCHEMBL11102137 | 1.00 | KIF11 (0.43) | KIF11HTTNR4A1NR4A2NR4A3 | |
| SCHEMBL27415070 | 0.78 | KIF11 (0.45) | KIF11MAPTKMT2A | |
| SCHEMBL11101874 | 0.74 | KDM4E (0.39) | KIF11 | |
| SCHEMBL11101870 | 0.74 | KDM4E (0.39) | KIF11 | |
| SCHEMBL11101876 | 0.74 | KDM4E (0.39) | KIF11 | |
| SCHEMBL22966169 | 0.73 | CYP1A2 (0.44) | KIF11MAPTKMT2ADNMT1 | |
| SCHEMBL4599455 | 0.72 | KIF11 (0.41) | KIF11MAPTKMT2A | |
| SCHEMBL6946184 | 0.71 | HTT (0.46) | HTTNR4A2MAPTKMT2A | |
| SCHEMBL6946186 | 0.71 | HTT (0.46) | HTTNR4A2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105658-A1 | Beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1984-04-18 | — | — | EP | disclosed |