Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 15/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101874 | 1.00 | KDM4E (0.39) | KDM4EKIF11CHRM2CHRM1CHRM3 | |
| SCHEMBL11101870 | 1.00 | KDM4E (0.39) | KDM4EKIF11CHRM2CHRM1CHRM3 | |
| SCHEMBL11102133 | 0.74 | KIF11 (0.43) | KIF11 | |
| SCHEMBL11102137 | 0.74 | KIF11 (0.43) | KIF11 | |
| SCHEMBL11102138 | 0.74 | KIF11 (0.43) | KIF11 | |
| SCHEMBL27415070 | 0.70 | KIF11 (0.45) | KIF11CYP2C19HIF1A | |
| SCHEMBL7156969 | 0.70 | KIF11 (0.38) | KIF11 | |
| SCHEMBL929816 | 0.67 | KIF11 (0.41) | KIF11CYP2C19HIF1A | |
| SCHEMBL12944446 | 0.66 | KIF11 (0.52) | KIF11 | |
| SCHEMBL11102402 | 0.65 | KIF11 (0.38) | KDM4EKIF11CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105658-A1 | Beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1984-04-18 | — | — | EP | disclosed |