Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102408 | 1.00 | KIF11 (0.38) | KIF11KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31304960 | 0.80 | KIF11 (0.38) | KIF11KDM4E | |
| SCHEMBL1648411 | 0.72 | KIF11 (0.38) | KIF11 | |
| SCHEMBL1648409 | 0.72 | KIF11 (0.38) | KIF11 | |
| SCHEMBL11102680 | 0.72 | HDAC3 (0.42) | KIF11CYP1A2CYP2C19DNMT1 | |
| SCHEMBL11102685 | 0.72 | HDAC3 (0.42) | KIF11CYP1A2CYP2C19DNMT1 | |
| SCHEMBL18764587 | 0.72 | KIF11 (0.52) | KIF11 | |
| SCHEMBL18764590 | 0.72 | KIF11 (0.52) | KIF11 | |
| SCHEMBL11850022 | 0.68 | KDM4E (0.63) | KIF11KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10345826 | 0.68 | ALDH1A1 (0.47) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105658-A1 | Beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1984-04-18 | — | — | EP | disclosed |