Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213874 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6830022 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3669161 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19156397 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3046110 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27876896 | 0.90 | G6PD (0.57) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3988193 | 0.88 | G6PD (0.58) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3122440 | 0.88 | G6PD (0.72) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11350178 | 0.88 | G6PD (0.72) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9623226 | 0.88 | G6PD (0.56) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424159-A | Process for the synthesis of the hydroxyacetyl side-chain of steroids of the pregnane type, novel 21-hydroxy-20-oxo-17α-pregnane compounds and pharmaceutical preparations containing them | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0005758-B1 | PROCESS FOR THE SYNTHESIS OF THE HYDROXYACETYL SIDE CHAIN OF PREGNANE STEROIDS, 21-HYDROXY 20-OXO-17 ALPHA PREGNANES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| EP-0005758-A1 | Process for the synthesis of the hydroxyacetyl side chain of pregnane steroids, 21-hydroxy 20-oxo-17 alpha pregnanes and pharmaceutical preparations containing them | CIBA-GEIGY AG (CH) | 1979-12-12 | — | — | EP | disclosed |