Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213874 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6830022 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19156397 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3046110 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11103160 | 1.00 | G6PD (0.71) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27876896 | 0.90 | G6PD (0.57) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3988193 | 0.88 | G6PD (0.58) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3122440 | 0.88 | G6PD (0.72) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11350178 | 0.88 | G6PD (0.72) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9623226 | 0.88 | G6PD (0.56) | G6PDKMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424159-A | Process for the synthesis of the hydroxyacetyl side-chain of steroids of the pregnane type, novel 21-hydroxy-20-oxo-17α-pregnane compounds and pharmaceutical preparations containing them | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | claimed |
| JP-52148687-A | — | — | None | — | — | JP | disclosed |
| CN-119950517-A | Ganaxolone for the treatment of tuberous sclerosis | 马瑞纳斯制药公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114828889-B | Ganaxolone for the treatment of tuberous sclerosis | 马瑞纳斯制药公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2015075693-A1 | PROCESS FOR THE SYNTHESIS OF (11 BETA.17ALPHA)-17-ACETOXY-1 1 -METHYL-19-NORPREGN-4-EN-3.20-DIONE | RICHTER GEDEON NYRT. (HU) | 2015-05-28 | — | — | WO | disclosed |
| EP-2155204-A1 | ANDROSTANE AND PREGNANE STEROIDS WITH POTENT ALLOSTERIC GABA RECEPTOR CHLORIDE IONOPHORE MODULATING PROPERTIES | Cook, Kevin M. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008157460-A1 | ANDROSTANE AND PREGNANE STEROIDS WITH POTENT ALLOSTERIC GABA RECEPTOR CHLORIDE IONOPHORE MODULATING PROPERTIES | COOK, KEVIN, M. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20070270584-A1 | Process for the Preparation of Steroidal Carbothioic Acid Derivatives and Intermediates | AXELLIA PHARMACEUTICALS APS (DK) | 2007-11-22 | — | — | US | disclosed |
| EP-1611149-A1 | PROCESS FOR THE PREPARATION OF STEROIDAL CARBOTHIOIC ACID DERIVATIVES AND INTERMEDIATES | Alpharma APS (DK) | 2006-01-04 | — | — | EP | disclosed |
| US-20050070515-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2005-03-31 | — | — | US | disclosed |
| US-4424159-A | Process for the synthesis of the hydroxyacetyl side-chain of steroids of the pregnane type, novel 21-hydroxy-20-oxo-17α-pregnane compounds and pharmaceutical preparations containing them | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| US-4424159-A | Process for the synthesis of the hydroxyacetyl side-chain of steroids of the pregnane type, novel 21-hydroxy-20-oxo-17α-pregnane compounds and pharmaceutical preparations containing them | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0005758-B1 | PROCESS FOR THE SYNTHESIS OF THE HYDROXYACETYL SIDE CHAIN OF PREGNANE STEROIDS, 21-HYDROXY 20-OXO-17 ALPHA PREGNANES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| US-4335121-A | TOPICAL ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1982-06-15 | — | — | US | disclosed |
| US-4189431-A | CYCLIZATION OF POLYENINE TO POLYCYCLIC COMPOUND HAVING CYCLOPENTANO RING | The Board of Trustees of Leland Stanford Junior University (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0005758-A1 | Process for the synthesis of the hydroxyacetyl side chain of pregnane steroids, 21-hydroxy 20-oxo-17 alpha pregnanes and pharmaceutical preparations containing them | CIBA-GEIGY AG (CH) | 1979-12-12 | — | — | EP | disclosed |
| JP-S52148687-A | PREPARATION OF 17-ESTERS OF PREGNANES | TAISHO PHARMACEUT CO LTD | 1977-12-10 | — | — | JP | disclosed |
| US-4033995-A | D-homo steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |
| US-4008312-A | Pregnane-21-oic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | disclosed |
| US-3956347-A | Novel pregnanoic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270584-A1 | Process for the Preparation of Steroidal Carbothioic Acid Derivatives and Intermediates | CYP17A1, HSD17B7, NR5A1 | G6PD 1899/4885KMT2A 2780/4885CYP1A2 65/4885 |
| US-20050070515-A1 | Compounds | LCT, LPO, LIPE | G6PD 47/4885KMT2A 3356/4885CYP1A2 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.