Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GBA1 | P04062 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110282 | 0.99 | ALDH1A1 (0.40) | ALDH1A1GBA1L3MBTL1TSHRHPGD | |
| SCHEMBL11103525 | 0.90 | ALDH1A1 (0.40) | ALDH1A1TSHRHPGDGLAGAA | |
| SCHEMBL11101954 | 0.83 | KDM4E (0.30) | ALDH1A1KDM4E | |
| SCHEMBL11111857 | 0.83 | HTR2A (0.46) | ALDH1A1GBA1HTR2AHRH1HRH4 | |
| SCHEMBL11107790 | 0.81 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL11104195 | 0.80 | HRH1 (0.51) | ALDH1A1L3MBTL1TSHRHPGDGLA | |
| SCHEMBL11106652 | 0.80 | HRH1 (0.51) | ALDH1A1L3MBTL1TSHRHPGDGLA | |
| SCHEMBL11109506 | 0.80 | HTR1A (0.32) | — | |
| Maleic Acid SCHEMBL11102533 | 0.79 | HTR2A (0.39) | ALDH1A1GBA1HTR2AKDM4EMAPK1 | |
| Fumaric Acid SCHEMBL11109417 | 0.79 | HTR2A (0.39) | ALDH1A1GBA1HTR2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435566-A | HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY | MARUKO SEIYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |