Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.63 |
| ▸ | RXRA | P19793 | 3/20 | 0.62 |
| ▸ | RXRB | P28702 | 3/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330795 | 0.93 | ALDH1A1 (1.00) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL19901 | 0.93 | ALDH1A1 (1.00) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL1330335 | 0.93 | ALDH1A1 (1.00) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| Dimethylamine SCHEMBL7283965 | 0.91 | ALDH1A1 (0.87) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL6911296 | 0.91 | ALDH1A1 (0.95) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL6907764 | 0.91 | ALDH1A1 (0.95) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL6915465 | 0.91 | ALDH1A1 (0.95) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL6909432 | 0.91 | ALDH1A1 (0.95) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| Ammonia Solution, Strong SCHEMBL22042012 | 0.91 | ALDH1A1 (0.95) | ALDH1A1SRD5A2RXRARXRBPLK1 | |
| SCHEMBL10547845 | 0.91 | ALDH1A1 (0.95) | ALDH1A1SRD5A2RXRARXRBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430326-A | Method of diminishing glucose levels resulting from endogenous glucagon | UNIVERSITY PATENTS, INC. (US) | 1984-02-07 | — | — | US | disclosed |