Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791806 | 0.84 | CYP1A2 (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8893987 | 0.84 | FAAH (0.49) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8621900 | 0.83 | ALDH1A1 (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11244901 | 0.81 | — | — | |
| SCHEMBL8866700 | 0.81 | GAA (0.43) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL16239754 | 0.81 | ATM (0.50) | ALDH1A1TSHRTDP1HCAR2NPSR1 | |
| SCHEMBL4366939 | 0.81 | NR1I2 (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10892991 | 0.80 | MGAM (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27629506 | 0.80 | CYP1A2 (0.47) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10892994 | 0.80 | MGAM (0.46) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051020-B1 | SUBSTITUTED AZOBICYCLOOCTANECARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION UND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR (FR) | 1984-08-08 | — | — | EP | claimed |