Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163489 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| SCHEMBL2350189 | 0.65 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| SCHEMBL29623192 | 0.65 | ALDH1A1 (0.67) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| SCHEMBL28574 | 0.65 | ALDH1A1 (0.67) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| SCHEMBL30442890 | 0.65 | ALDH1A1 (0.67) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| SCHEMBL15055208 | 0.64 | — | — | |
| Hydrogen Sulfide SCHEMBL20536042 | 0.63 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| Catechol SCHEMBL21408977 | 0.63 | ALDH1A1 (0.71) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| SCHEMBL7845497 | 0.63 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 | |
| Potassium SCHEMBL30932291 | 0.63 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10BCL2L1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121082-A1 | Guanidin derivatives | BAYER AG (DE) | 1984-10-10 | — | — | EP | disclosed |