SCHEMBL2350189

SCHEMBL2350189

Oc1ccccc1C1=CC=CC[CH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
BCL2L1 Q07817 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
CA12 O43570 1/20 0.33
GMNN O75496 1/20 0.33
EGFR P00533 1/20 0.33
CA2 P00918 1/20 0.33
LMNA P02545 1/20 0.33
FYN P06241 1/20 0.33
POLB P06746 1/20 0.33
CA3 P07451 1/20 0.33
CYP3A4 P08684 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041001 0.71 ALDH1A1 (0.35) ALDH1A1MAPTLMNA
SCHEMBL17593572 0.70 HSD11B1 (0.36) ALDH1A1RAB9AKDM4ELMNAPOLB
SCHEMBL11074497 0.68 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL9307560 0.68
SCHEMBL6047661 0.67 AHR (0.33)
Water SCHEMBL27738150 0.67 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL27365125 0.65 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL11106965 0.65 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL28574 0.65 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL30442890 0.65 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2528979-A1 EPOXY-BASED PRIMER COMPOSITIONS Hempel A/S (DK) 2012-12-05 EP disclosed
WO-2011092278-A1 EPOXY-BASED PRIMER COMPOSITIONS HEMPEL A/S (DK) 2011-08-04 WO disclosed