Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11109003 | 0.98 | HTR2C (0.43) | HTR2CHTR2AMAOBHTR2BCYP19A1 | |
| SCHEMBL11105723 | 0.85 | HTR2C (0.38) | HTR2CHTR2AMAOBHTR2BSLC6A4 | |
| SCHEMBL11112740 | 0.83 | HTR2A (0.42) | HTR2CHTR2AALDH1A1MAPTALOX12 | |
| SCHEMBL11105016 | 0.82 | HTR2A (0.50) | HTR2CHTR2AMAOBCYP19A1AR | |
| SCHEMBL11104139 | 0.82 | AR (0.47) | HTR2AMAOBCYP19A1ALDH1A1MAPT | |
| SCHEMBL11113079 | 0.82 | AR (0.45) | HTR2CHTR2AHTR2BCYP19A1PGR | |
| Hydrochloric Acid SCHEMBL11112345 | 0.81 | AR (0.44) | HTR2CHTR2AHTR2BCYP19A1PGR | |
| SCHEMBL11110129 | 0.80 | APEX1 (0.47) | CYP19A1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11108436 | 0.80 | CYP1A2 (0.39) | HTR2CHTR2AHTR2BMAPT | |
| SCHEMBL11111134 | 0.78 | KDM4E (0.48) | HTR2AMAOBCYP19A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |