Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11112345 | 0.98 | AR (0.44) | ARHTR2AHTR2CHTR2BS100A4 | |
| SCHEMBL11112650 | 0.85 | HTR2A (0.37) | ARHTR2AHTR2CHTR2BS100A4 | |
| SCHEMBL11112740 | 0.83 | HTR2A (0.42) | ARHTR2AHTR2CS100A4KCNH2 | |
| SCHEMBL11105016 | 0.82 | HTR2A (0.50) | ARHTR2AHTR2CCYP19A1HSD17B10 | |
| SCHEMBL11106968 | 0.82 | HTR2C (0.41) | ARHTR2AHTR2CHTR2BCYP19A1 | |
| SCHEMBL11104139 | 0.82 | AR (0.47) | ARHTR2ACYP19A1MAPK1 | |
| Hydrochloric Acid SCHEMBL11109003 | 0.81 | HTR2C (0.43) | ARHTR2AHTR2CHTR2BCYP19A1 | |
| SCHEMBL11111155 | 0.80 | APEX1 (0.47) | ARPSMD14POLBL3MBTL1ALOX15 | |
| SCHEMBL11111134 | 0.78 | KDM4E (0.48) | ARHTR2ACYP19A1MAPK1POLB | |
| SCHEMBL11107702 | 0.78 | AR (0.38) | ARHTR2AHTR2CHTR2BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |