Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 12/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105297 | 0.84 | GALR3 (0.60) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL11100649 | 0.81 | GALR3 (0.57) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL11104368 | 0.81 | GALR3 (0.57) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL11109199 | 0.79 | EGFR (0.48) | EGFRAURKARPS6KB1AURKBKRAS | |
| SCHEMBL11112352 | 0.76 | MAOA (0.48) | LMNAHSD17B10 | |
| SCHEMBL11101615 | 0.75 | GALR3 (0.57) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL31505705 | 0.74 | GALR3 (0.72) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL31505701 | 0.74 | GALR3 (0.72) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL13283262 | 0.74 | GALR3 (0.72) | GALR3NR2F2EGFRTNFRAB9A | |
| SCHEMBL11012849 | 0.73 | EGFR (0.50) | EGFRRAB9AHSD17B10AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57176967-A | — | — | None | — | — | JP | disclosed |
| JP-59036666-A | — | — | None | — | — | JP | disclosed |
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| JP-S5936666-A | AMINOPYRIMIDINE DERIVATIVE | SANKYO CO LTD | 1984-02-28 | — | — | JP | disclosed |
| JP-S57176967-A | AMINOPYRIMIDINE DERIVATIVE AND ANTIBACTERIAL, INSECTICIDAL AND MITICIDAL AGENT | SANKYO CO LTD | 1982-10-30 | — | — | JP | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |