Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 5/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | SHBG | P04278 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413691 | 1.00 | SERPINA6 (0.64) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9862493 | 0.88 | HSD17B10 (0.71) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9862485 | 0.88 | HSD17B10 (0.71) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9193196 | 0.86 | FNTA (0.73) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9193185 | 0.86 | FNTA (0.73) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8755727 | 0.86 | SERPINA6 (0.80) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9221947 | 0.86 | SERPINA6 (0.80) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10868078 | 0.86 | SERPINA6 (0.80) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11794803 | 0.86 | HIF1A (0.74) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8013392 | 0.86 | HIF1A (0.74) | SERPINA6LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |
| US-4224320-A | Novel steroids of the pregnane series, substituted in the 17-position, their manufacture and their use | SCHERING, AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| US-4207316-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |