Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.71 |
| ▸ | SHBG | P04278 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862493 | 1.00 | HSD17B10 (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL10868078 | 0.89 | SERPINA6 (0.80) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL8755727 | 0.89 | SERPINA6 (0.80) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL9221947 | 0.89 | SERPINA6 (0.80) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11109164 | 0.88 | SERPINA6 (0.64) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11413691 | 0.88 | SERPINA6 (0.64) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11845386 | 0.85 | HSD17B10 (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11852315 | 0.85 | HSD17B10 (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11845368 | 0.85 | HSD17B10 (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA | |
| SCHEMBL11684609 | 0.84 | HSD17B10 (0.69) | HSD17B10SHBGSMN1; SMN2SERPINA6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021404-A | Angiostatic collagen modulators | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4994443-A | Administering heparin or a derivative thereof and a steroid | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0019162-A1 | 12-Alpha-hydroxy steroids and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-11-26 | — | — | EP | disclosed |