Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 6/20 | 0.80 |
| ▸ | SHBG | P04278 | 8/20 | 0.69 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.69 |
| ▸ | BLM | P54132 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | PGR | P06401 | 3/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868078 | 1.00 | SERPINA6 (0.80) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL9221947 | 1.00 | SERPINA6 (0.80) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL11682243 | 0.89 | SERPINA6 (1.00) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL3052566 | 0.89 | SERPINA6 (1.00) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL26178 | 0.89 | SERPINA6 (1.00) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL9862493 | 0.89 | HSD17B10 (0.71) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL9862485 | 0.89 | HSD17B10 (0.71) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL7989813 | 0.88 | SERPINA6 (0.69) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| SCHEMBL7989808 | 0.88 | SERPINA6 (0.69) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 | |
| Acetic Acid SCHEMBL28423891 | 0.87 | SERPINA6 (0.96) | SERPINA6SHBGLMNASMN1; SMN2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402963-B1 | 17-Alpha ethynyl steroids | UPJOHN CO (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1995002424-A1 | LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN | NORDION INTERNATIONAL INC. (CA) | 1995-01-26 | — | — | WO | disclosed |
| EP-0308412-B1 | 16$g(a)-METHYLATION PROCESS | THE UPJOHN COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| EP-0148616-B1 | STABILISED MONOLITHIUM ACETYLIDE AND THE ETHYNYLATION OF STEROIDS | THE UPJOHN COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4990612-A | 16α-methylation process | THE UPJOHN COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0402963-A2 | 17-Alpha ethynyl steroids | THE UPJOHN COMPANY (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4929395-A | 16α-methylation process | THE UPJOHN COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4891426-A | EPOXIDATION WITH PERACID | THE UPJOHN COMPANY (US) | 1990-01-02 | — | — | US | disclosed |
| EP-0308412-A1 | 16-g(a)-METHYLATION PROCESS. | UPJOHN CO (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0276393-A2 | Process for the preparation of 6-alpha, 9-alpha-difluoro-11-beta-17-alpha-dihydroxy-16-alpha-methyl-pregn-4-ene-3,20-dione and its derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-08-03 | — | — | EP | disclosed |
| WO-1987007612-A1 | 16alpha-METHYLATION PROCESS | THE UPJOHN COMPANY (US) | 1987-12-17 | — | — | WO | disclosed |
| US-4704455-A | 16α-methylatedΔ17(20)-corticoids | THE UPJOHN COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| US-4618456-A | Ethynylation of 16-methyl-17-keto steroids | THE UPJOHN COMPANY (US) | 1986-10-21 | — | — | US | disclosed |
| US-4567001-A | 16-Methylene-17α-hydroxy-progesterones | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0148616-A2 | Stabilised monolithium acetylide and the ethynylation of steroids | THE UPJOHN COMPANY (US) | 1985-07-17 | — | — | EP | disclosed |
| US-4526720-A | Process to prepare stabilized monolithium acetylide | THE UPJOHN COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |