Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HTR3A | P46098 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TOP2A | P11388 | 3/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637041 | 0.99 | KDM4E (0.41) | KDM4EHTR3AALDH1A1TOP2ATOP2B | |
| SCHEMBL9416403 | 0.89 | KDM4E (0.41) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL11114605 | 0.84 | PIK3CG (0.42) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL6217185 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL29766836 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL2744582 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL28458144 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| Hydrochloric Acid SCHEMBL6004997 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10514291 | 0.81 | PIK3CD (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10862667 | 0.81 | KDM4E (0.60) | KDM4EHTR3AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |