Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TOP2A | P11388 | 4/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240583 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10875722 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10923486 | 0.90 | KDM4E (0.47) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL8131496 | 0.89 | KDM4E (0.40) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10591014 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9370629 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9370160 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL6660578 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL7501881 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9234576 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1TOP2ATOP2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | claimed |
| EP-1236718-B1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER CHEMICALS AG (DE) | 2004-08-11 | — | — | EP | claimed |
| EP-1236718-A1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER AG (DE) | 2002-09-04 | — | — | EP | claimed |
| EP-0775114-B1 | PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS | PROCTER & GAMBLE (US) | 2000-03-22 | — | — | EP | claimed |
| EP-0274033-B1 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1992-03-11 | — | — | EP | claimed |
| EP-0274033-A1 | Process for the preparation of quinolinecarboxylic acids | BAYER AG (DE) | 1988-07-13 | — | — | EP | claimed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| EP-0757990-B1 | 7-(1-Pyrrolidoinyl)-3-quinolone and naphthyridone carboxylic acid derivatives, method for their preparation and for substituted mono- and bicyclic pyrrolidine intermediates, and their antibacterial and feed additive compositions | BAYER HEALTHCARE AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| EP-1236718-B1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER CHEMICALS AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| EP-1236718-A1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER AG (DE) | 2002-09-04 | — | — | EP | disclosed |
| EP-0704443-B1 | Quinolone and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 2000-12-27 | — | — | EP | disclosed |
| EP-0401623-B1 | Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0224178-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0203488-A2 | 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acids and 1,8-naphthyridine carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |
| EP-0113091-B1 | MICROBIOCIDAL AGENTS BASED ON QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0169993-A2 | 7-(3-Aryl-1-piperazinyl) and 7-(3-cyclohexyl-1-piperazinyl) 3-quinoline carboxylic acids | BAYER AG (DE) | 1986-02-05 | — | — | EP | disclosed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0166939-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7(3-oxo-1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0113091-A1 | Microbiocidal agents based on quinolone-carboxylic acids | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |