Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585649 | 0.85 | ALDH1A1 (0.53) | POLBALDH1A1MRGPRX4TDP1KMT2A | |
| SCHEMBL10918166 | 0.85 | CDK2 (0.47) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL11092742 | 0.82 | HPGD (0.56) | LMNAALDH1A1CDK2KMT2AMEN1 | |
| SCHEMBL30539397 | 0.80 | TDP1 (0.64) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL8304645 | 0.80 | TDP1 (0.64) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL9863812 | 0.80 | TDP1 (0.64) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| Propylamine SCHEMBL10889604 | 0.80 | ALDH1A1 (0.48) | POLBALDH1A1CDK2MRGPRX4TDP1 | |
| Monoethanolamine SCHEMBL10891249 | 0.79 | ALDH1A1 (0.50) | POLBALDH1A1CDK2MRGPRX4TDP1 | |
| SCHEMBL27592434 | 0.79 | TDP1 (0.63) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL29740471 | 0.79 | PKM (0.59) | KDM4EPOLBLMNAALDH1A1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435588-A | 2'-CHLORO-4'-TRIFLUOROMETHYL-PHENOXY-3-BENZOATE DERIVATIVES | GAF CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |