Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.41 |
| ▸ | PDE5A | O76074 | 4/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112216 | 0.90 | GPR35 (0.44) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11132941 | 0.89 | GPR35 (0.43) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11113502 | 0.83 | GPR35 (0.51) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11104343 | 0.78 | GPR35 (0.46) | GPR35CYSLTR2CYSLTR1KMT2AMEN1 | |
| SCHEMBL9847122 | 0.77 | GPR35 (0.54) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11111716 | 0.76 | ABCB11 (0.52) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11288378 | 0.75 | PDE5A (0.44) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11109052 | 0.74 | GPR35 (0.54) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11285738 | 0.73 | GPR35 (0.42) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 | |
| SCHEMBL11284294 | 0.73 | MEN1 (0.53) | ABCB11GPR35PDE5ACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104018-A2 | Benzopyran, benzothiapyran and quinoline compounds and pharmaceutical compositions containing them | FISONS plc (GB) | 1984-03-28 | — | — | EP | claimed |
| EP-0104018-A2 | Benzopyran, benzothiapyran and quinoline compounds and pharmaceutical compositions containing them | FISONS plc (GB) | 1984-03-28 | — | — | EP | disclosed |