Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RNF4 | P78317 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863632 | 0.86 | ALDH1A1 (0.66) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL8378909 | 0.80 | TDP1 (0.76) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL4339458 | 0.78 | TP53 (0.60) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| Ethane SCHEMBL27359121 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL10622818 | 0.74 | TP53 (0.41) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL31199167 | 0.74 | TP53 (0.50) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL27352642 | 0.74 | TP53 (0.64) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL9614304 | 0.73 | ALDH1A1 (0.64) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL9066705 | 0.73 | TP53 (0.51) | ALDH1A1TP53TDP1CYP3A4KMT2A | |
| SCHEMBL10627183 | 0.73 | PAX8 (0.43) | ALDH1A1TP53TDP1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060423-B1 | 2-PYRIDYLOXYACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |