Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108419 | 0.84 | CYP1A2 (0.44) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL11112729 | 0.83 | ALDH1A1 (0.39) | KMT2ATDP1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11109132 | 0.83 | ALDH1A1 (0.47) | MAPTKMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL11106321 | 0.83 | ALDH1A1 (0.50) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL11106958 | 0.82 | MAPT (0.40) | MAPTKMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL11113025 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL11107922 | 0.81 | MAPT (0.43) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL11107315 | 0.81 | CYP1A2 (0.39) | MAPTKMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL16209980 | 0.80 | MAPT (0.44) | MAPTKMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL11112916 | 0.79 | MAPT (0.46) | MAPTKMT2ATDP1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |