SCHEMBL11110682

SCHEMBL11110682

COCOc1ccc(C(C)(C)CC(C)(C)C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
SHBG P04278 1/20 0.50
MDH1 P40925 13/20 0.46
MDH2 P40926 13/20 0.46
HIF1A Q16665 4/20 0.44
MEN1 O00255 2/20 0.44
APAF1 O14727 2/20 0.44
USP2 O75604 2/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
ERBB2 P04626 2/20 0.44
TP53 P04637 2/20 0.44
FYN P06241 2/20 0.44
CHRM2 P08172 2/20 0.44
CHRM4 P08173 2/20 0.44
CHRM5 P08912 2/20 0.44
ADRA2A P08913 2/20 0.44
MAPT P10636 2/20 0.44
HSPD1 P10809 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11110656 0.84 CYP3A4 (0.60) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL23703947 0.84 CYP3A4 (0.60) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL11125566 0.84 CYP3A4 (0.70) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL11127186 0.82 CYP3A4 (0.58) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL1257955 0.81 SMN1; SMN2 (0.66) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL2129443 0.80 SMN1; SMN2 (0.53) SMN1; SMN2MEN1ALDH1A1LMNATP53
SCHEMBL12926334 0.80 MEN1 (0.50) CYP3A4SMN1; SMN2HIF1AMEN1ALDH1A1
SCHEMBL7166618 0.80 CYP3A4 (0.59) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL4314095 0.80 CYP3A4 (0.64) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL338553 0.79 CYP3A4 (0.64) CYP3A4SMN1; SMN2SHBGMDH1MDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252574-B2 Bis-phenyl-phenoxy polyolefin procatalysts having two anthracenyl ligands DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-18 US disclosed
EP-3601388-B1 BIS-BIPHENYL-PHENOXY CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-08-07 EP disclosed
US-20240084050-A1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-14 US disclosed
EP-3844193-B1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-01-03 EP disclosed
US-11401354-B2 Bis-biphenyl-phenoxy catalysts for olefin polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-02 US disclosed
EP-3356430-B1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-22 EP disclosed
US-20210309768-A1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-07 US disclosed
US-20210309768-A1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-07 US disclosed
EP-3844193-A1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS Dow Global Technologies LLC (US) 2021-07-07 EP disclosed
CN-108377649-B Polymerization process for producing ethylene-based polymers 陶氏环球技术有限责任公司 2021-04-23 CN disclosed
CN-112585172-A Bis-phenylphenoxy polyolefin procatalysts with two anthracene-based ligands 陶氏环球技术有限责任公司 2021-03-30 CN disclosed
US-10647797-B2 Polymerization process for producing ethylene based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-12 US disclosed
WO-2020047384-A1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-05 WO disclosed
WO-2020047384-A1 BIS-PHENYL-PHENOXY POLYOLEFIN PROCATALYSTS HAVING TWO ANTHRACENYL LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-05 WO disclosed
EP-3601388-A1 BIS-BIPHENYL-PHENOXY CATALYSTS FOR OLEFIN POLYMERIZATION Dow Global Technologies LLC (US) 2020-02-05 EP disclosed
US-20180282452-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-04 US disclosed
WO-2018183700-A1 BIS-BIPHENYL-PHENOXY CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-04 WO disclosed
EP-3356430-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS Dow Global Technologies LLC (US) 2018-08-08 EP disclosed
EP-0102324-A2 Lipids and surfactants in an aqueous medium CIBA-GEIGY AG (CH) 1984-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252574-B2 Bis-phenyl-phenoxy polyolefin procatalysts having two anthracenyl ligands PARG, PARN, SOD1 CYP3A4 558/4885SMN1; SMN2 3621/4885SHBG 4227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.