SCHEMBL338553

SCHEMBL338553

[CH2]COc1ccc(C(C)(C)CC(C)(C)C)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
SHBG P04278 1/20 0.52
MDH1 P40925 11/20 0.47
MDH2 P40926 11/20 0.47
HIF1A Q16665 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
APAF1 O14727 2/20 0.45
USP2 O75604 2/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 2/20 0.45
ERBB2 P04626 2/20 0.45
TP53 P04637 2/20 0.45
FYN P06241 2/20 0.45
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRM5 P08912 2/20 0.45
ADRA2A P08913 2/20 0.45
MAPT P10636 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11127186 0.87 CYP3A4 (0.58) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL3255330 0.84 SMN1; SMN2 (0.64) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL1257955 0.82 SMN1; SMN2 (0.66) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL11110656 0.81 CYP3A4 (0.60) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL11125563 0.80 CYP3A4 (0.68) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL13019868 0.80 CYP3A4 (0.58) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL988235 0.80 CYP3A4 (0.58) CYP3A4SMN1; SMN2SHBGMDH1MDH2
SCHEMBL17491754 0.79 ALDH1A1 (0.52) CYP3A4SMN1; SMN2HIF1AMEN1KMT2A
SCHEMBL3141888 0.79 SMN1; SMN2 (0.55) SMN1; SMN2MEN1KMT2AALDH1A1LMNA
SCHEMBL28747587 0.79 CYP3A4 (0.61) CYP3A4SMN1; SMN2SHBGMDH1MDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117883308-A Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate 莱雅公司 2024-04-16 CN disclosed
EP-4262719-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE CITRIC ACID ESTER L'OREAL (FR) 2023-10-25 EP disclosed
EP-4262714-A1 COSMETIC COMPOSITION COMPRISING A MEROCYANINE, A TRIAZINE UV-SCREENING AGENT, AND A POLYSACCHARIDE MODIFIED WITH HYDROPHOBIC CHAINS L'OREAL (FR) 2023-10-25 EP disclosed
US-11679069-B2 Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate L'OREAL (FR) 2023-06-20 US disclosed
WO-2022129059-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE CITRIC ACID ESTER L'OREAL (FR) 2022-06-23 WO disclosed
WO-2022129039-A1 COSMETIC COMPOSITION COMPRISING A MEROCYANINE, A TRIAZINE UV-SCREENING AGENT, AND A POLYSACCHARIDE MODIFIED WITH HYDROPHOBIC CHAINS L'OREAL (FR) 2022-06-23 WO disclosed
US-20210251868-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE L'OREAL (FR) 2021-08-19 US disclosed
EP-3827807-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE N-SUBSTITUTED AMIDE L'OREAL (FR) 2021-06-02 EP disclosed
US-11000460-B2 Cosmetic or dermatological composition comprising a merocyanine, an oily phase and a C1—C4 monoalkanol L'OREAL (FR) 2021-05-11 US disclosed
EP-3813779-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE L'OREAL SA (FR) 2021-05-05 EP disclosed
WO-2005058269-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-06-30 WO disclosed
WO-2004085412-A2 SYMMETRICAL TRIAZINE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-10-07 WO disclosed
US-20040191191-A1 Symmetrical triazine derivatives CIBA SPECIALTY CHEMICALS CORP. 2004-09-30 US disclosed
WO-2004052837-A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-24 WO disclosed
WO-2004006878-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-22 WO disclosed
US-4551420-A ULTRAVIOLET RAY ABSORBING POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-11-05 US disclosed
US-4464462-A ULTRAVIOLET RAY-ABSORBING ACRYLIC POLYMER LATEX; ANTISTATIC AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-08-07 US disclosed
US-4455368-A Silver halide photographic light-sensitive material containing a UV absorbing polymer latex FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
US-4443534-A VINYL CHLORIDE HOMO- OR COPOLYMER, OR ACRYLAMIDE OR ACRYLIC ESTER HOMO- OR COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1984-04-17 US disclosed
US-4062730-A PSEUDOMONAS FLUORESCENS Malkki, Yrjo (SF) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11679069-B2 Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate KRT18, DSG1, CUTA CYP3A4 3822/4885SMN1; SMN2 4057/4885SHBG 2061/4885
US-20210251868-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE KRT18, DSC1, DSG1 CYP3A4 3480/4885SMN1; SMN2 3998/4885SHBG 2738/4885
US-20040191191-A1 Symmetrical triazine derivatives H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RNF168, CYC1 CYP3A4 668/4885SMN1; SMN2 4354/4885SHBG 380/4885
US-11000460-B2 Cosmetic or dermatological composition comprising a merocyanine, an oily phase and a C1—C4 monoalkanol KRT18, C1S, C1R CYP3A4 1866/4885SMN1; SMN2 4497/4885SHBG 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.