SCHEMBL11110809

SCHEMBL11110809

CCC(N)Cc1ccc(C(N)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.53
ANPEP P15144 2/20 0.50
ENPEP Q07075 2/20 0.50
PLA2G10 O15496 1/20 0.47
PLA2G2A P14555 1/20 0.47
PARP10 Q53GL7 5/20 0.46
TPH1 P17752 1/20 0.42
DPP4 P27487 4/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PARP1 P09874 1/20 0.41
PARP2 Q9UGN5 1/20 0.41
PARP4 Q9UKK3 1/20 0.41
CYP17A1 P05093 1/20 0.41
EPHX2 P34913 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18930227 0.85 ANPEP (0.53) SLC6A4ANPEPENPEPPLA2G10PLA2G2A
Hydrochloric Acid SCHEMBL21144942 0.83 ANPEP (0.51) SLC6A4ANPEPENPEPPLA2G10PLA2G2A
Hydrochloric Acid SCHEMBL21144940 0.83 ANPEP (0.51) SLC6A4ANPEPENPEPPLA2G10PLA2G2A
SCHEMBL14023887 0.81 ANPEP (0.50) SLC6A4ANPEPENPEPPLA2G10PLA2G2A
SCHEMBL19523213 0.81 PLA2G10 (0.47) PLA2G10PLA2G2APARP10DPP4CA1
SCHEMBL6764390 0.81 TAAR1 (0.59) SLC6A4PLA2G10PLA2G2A
SCHEMBL9392575 0.81 TAAR1 (0.59) SLC6A4PLA2G10PLA2G2A
SCHEMBL8745472 0.81 TAAR1 (0.59) SLC6A4PLA2G10PLA2G2A
SCHEMBL28280179 0.81 LOXL2 (0.59) SLC6A4ANPEPENPEPDPP4CA1
Hydrochloric Acid SCHEMBL10623908 0.80 PLA2G10 (0.46) PLA2G10PLA2G2APARP10DPP4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104888-A1 Process for preparing 2-hydroxy-2-phenylethylamines ELI LILLY AND COMPANY (US) 1984-04-04 EP disclosed