Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764390 | 1.00 | TAAR1 (0.59) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL8745472 | 1.00 | TAAR1 (0.59) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL105246 | 0.86 | EPHX1 (0.61) | PLA2G10PLA2G2A | |
| SCHEMBL251733 | 0.84 | ANPEP (0.62) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL1048952 | 0.84 | TAAR1 (0.59) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL5183224 | 0.84 | ANPEP (0.62) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL8136474 | 0.84 | TAAR1 (0.59) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL2439514 | 0.84 | ANPEP (0.62) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL14236735 | 0.82 | EPHX1 (0.49) | PLA2G10PLA2G2A | |
| SCHEMBL20821081 | 0.82 | PLA2G10 (0.48) | PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | claimed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | disclosed |
| US-4585796-A | HYPOGLYCEMIC, ANTI-OBESITY | HOFFMANN-LA ROCHE INC. (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0101069-B1 | PHENETHANOL AMINES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-04-23 | — | — | EP | disclosed |
| EP-0101069-A1 | Phenethanol amines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-22 | — | — | EP | disclosed |