Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.69 |
| ▸ | FEN1 | P39748 | 2/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375341 | 0.87 | ERCC5 (0.54) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL10455392 | 0.84 | ERCC5 (0.67) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL5312318 | 0.84 | ERCC5 (0.67) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL8548986 | 0.84 | ERCC5 (0.67) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL28547033 | 0.83 | ERCC5 (0.66) | ERCC5FEN1PARP10SMN1; SMN2POLB | |
| SCHEMBL8341053 | 0.83 | ERCC5 (0.66) | ERCC5FEN1PARP10SMN1; SMN2POLB | |
| SCHEMBL4708458 | 0.83 | ERCC5 (0.65) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL9166340 | 0.81 | ERCC5 (0.63) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL11463053 | 0.81 | ERCC5 (0.63) | ERCC5FEN1AKR1C3HDAC8TNKS | |
| SCHEMBL9671290 | 0.81 | ERCC5 (0.63) | ERCC5FEN1AKR1C3HDAC8TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |