Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110885 | 0.87 | ERCC5 (0.69) | ERCC5FEN1AKR1C3PARP14PARP10 | |
| SCHEMBL11110229 | 0.83 | MMP1 (0.61) | ERCC5FEN1PARP14PARP10PARP15 | |
| SCHEMBL31590697 | 0.82 | AKR1C3 (0.77) | AKR1C3PARP14PARP10TNKSPARP15 | |
| SCHEMBL8783043 | 0.82 | AKR1C3 (0.77) | AKR1C3PARP14PARP10TNKSPARP15 | |
| SCHEMBL6518277 | 0.81 | PARP14 (0.58) | AKR1C3PARP14PARP10TNKSPARP15 | |
| SCHEMBL11840624 | 0.81 | MAOB (0.64) | AKR1C3PARP14PARP10TNKSPARP15 | |
| SCHEMBL27916079 | 0.81 | NR4A2 (0.74) | MRGPRX4NR4A2MAOAMAOBMEN1 | |
| SCHEMBL883109 | 0.78 | TNKS (0.58) | ERCC5FEN1AKR1C3PARP14PARP10 | |
| SCHEMBL14191212 | 0.77 | SRD5A2 (0.58) | AKR1C3PARP14PARP10TNKSPARP15 | |
| SCHEMBL13250810 | 0.77 | SRD5A2 (0.58) | AKR1C3PARP14PARP10TNKSPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |