SCHEMBL8548986

SCHEMBL8548986

O=C(CCl)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.67
FEN1 P39748 1/20 0.67
AKR1C3 P42330 1/20 0.66
ALDH1A1 P00352 3/20 0.60
MAPK1 P28482 2/20 0.60
TRPA1 O75762 1/20 0.60
GSK3B P49841 1/20 0.60
HIF1A Q16665 1/20 0.60
HDAC8 Q9BY41 2/20 0.58
POLB P06746 2/20 0.56
MITF O75030 1/20 0.56
HTT P42858 1/20 0.56
NPC1 O15118 2/20 0.55
PKM P14618 1/20 0.52
TNKS O95271 1/20 0.51
PARP15 Q460N3 1/20 0.51
PARP14 Q460N5 1/20 0.51
PARP10 Q53GL7 1/20 0.51
TNKS2 Q9H2K2 1/20 0.51
PARP2 Q9UGN5 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL883109 0.92 TNKS (0.58) ERCC5FEN1AKR1C3ALDH1A1MAPK1
SCHEMBL11110885 0.84 ERCC5 (0.69) ERCC5FEN1AKR1C3ALDH1A1HDAC8
SCHEMBL1593331 0.84 GSK3B (0.67) ERCC5FEN1ALDH1A1MAPK1TRPA1
SCHEMBL10455392 0.83 ERCC5 (0.67) ERCC5FEN1AKR1C3ALDH1A1HDAC8
SCHEMBL5312318 0.83 ERCC5 (0.67) ERCC5FEN1AKR1C3ALDH1A1GSK3B
SCHEMBL4708458 0.81 ERCC5 (0.65) ERCC5FEN1AKR1C3ALDH1A1HDAC8
SCHEMBL7337987 0.81 NR4A2 (0.72)
SCHEMBL2379240 0.81 CES2 (0.65) ALDH1A1MAPK1TRPA1GSK3BHIF1A
SCHEMBL1193379 0.80 AKR1C3 (0.72) ERCC5FEN1AKR1C3ALDH1A1MAPK1
SCHEMBL11463053 0.80 ERCC5 (0.63) ERCC5FEN1AKR1C3ALDH1A1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1926473-B Inorganic paste composition, method for preparing inorganic paste composition, and sheet-shaped unbaked body for producing display panel TOKYO OHKA KOGYO CO LTD 2012-03-21 CN disclosed
CN-1926473-A Inorganic paste composition, method for preparing inorganic paste composition, and sheet-shaped unbaked body for producing display panel TOKYO OHKA KOGYO CO LTD (JP) 2007-03-07 CN disclosed
EP-0564924-B1 2-Oxoethyl derivatives as immunosuppressants BAYER AG (US) 1998-09-09 EP disclosed
US-5686424-A FOR TREATING INFLAMMATION MILES INC. (US) 1997-11-11 US disclosed
EP-0564924-A2 2-Oxoethyl derivatives as immunosuppressants Bayer Corporation (US) 1993-10-13 EP disclosed