Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GLUL | P15104 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129293 | 1.00 | SHBG (0.45) | SHBGCYP19A1MEN1KMT2ATDP1 | |
| SCHEMBL11110732 | 0.95 | CYP19A1 (0.44) | SHBGCYP19A1LMNAMAPTHSD17B10 | |
| SCHEMBL11126765 | 0.95 | CYP19A1 (0.44) | SHBGCYP19A1LMNAMAPTHSD17B10 | |
| SCHEMBL11095036 | 0.84 | SHBG (0.44) | SHBGCYP19A1MEN1KMT2ATDP1 | |
| SCHEMBL6706329 | 0.84 | SHBG (0.44) | SHBGCYP19A1LMNAMAPTHSD17B10 | |
| SCHEMBL11095042 | 0.84 | SHBG (0.44) | SHBGCYP19A1MEN1KMT2ATDP1 | |
| SCHEMBL6705617 | 0.83 | MEN1 (0.57) | SHBGCYP19A1MEN1KMT2ATDP1 | |
| SCHEMBL6705623 | 0.83 | MEN1 (0.57) | SHBGCYP19A1MEN1KMT2ATDP1 | |
| SCHEMBL11110788 | 0.83 | MEN1 (0.60) | SHBGCYP19A1MEN1KMT2ATDP1 | |
| SCHEMBL11114508 | 0.83 | MEN1 (0.60) | SHBGCYP19A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106793-A1 | 7-Alpha-alkyl-17-alpha-pregn-4-ene-21,17-carbolactones and -21-carboxylic acid salts and procedures for manufacturing them and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-04-25 | — | — | EP | claimed |