Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | GLUL | P15104 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095042 | 1.00 | SHBG (0.44) | SHBGNR3C1LMNAMAPTHSD17B10 | |
| SCHEMBL6708645 | 0.84 | AR (0.49) | SHBGNR3C1LMNAHSD17B10HIF1A | |
| SCHEMBL11027166 | 0.84 | AR (0.49) | SHBGNR3C1LMNAHSD17B10HIF1A | |
| SCHEMBL11111005 | 0.84 | SHBG (0.45) | SHBGNR3C1LMNAMAPTHSD17B10 | |
| SCHEMBL11027165 | 0.84 | AR (0.49) | SHBGNR3C1LMNAHSD17B10HIF1A | |
| SCHEMBL11129293 | 0.84 | SHBG (0.45) | SHBGNR3C1LMNAMAPTHSD17B10 | |
| SCHEMBL6706329 | 0.83 | SHBG (0.44) | SHBGNR3C1LMNAMAPTHSD17B10 | |
| SCHEMBL10947065 | 0.83 | AR (0.49) | SHBGNR3C1LMNAHSD17B10HIF1A | |
| SCHEMBL10955541 | 0.83 | AR (0.49) | SHBGNR3C1LMNAHSD17B10HIF1A | |
| SCHEMBL11110732 | 0.83 | CYP19A1 (0.44) | SHBGNR3C1LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450107-A | 7α-Alkoxycarbonyl-15β,16β-methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | claimed |
| US-4450107-A | 7α-Alkoxycarbonyl-15β,16β-methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |