Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | HTT | P42858 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115640 | 0.94 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11159262 | 0.92 | MAPT (0.71) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13745659 | 0.92 | MAPT (0.71) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8373327 | 0.91 | MAPT (1.00) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11118609 | 0.91 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3440754 | 0.90 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31519377 | 0.90 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11112058 | 0.89 | MAPT (0.67) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8284615 | 0.88 | MAPT (0.71) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10282556 | 0.88 | MAPT (0.78) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |