Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581290 | 0.95 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10578809 | 0.93 | MAPT (0.67) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1004459 | 0.89 | MAPT (0.77) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30468755 | 0.89 | MAPT (0.77) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11111034 | 0.88 | MAPT (0.83) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8373327 | 0.84 | MAPT (1.00) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31519377 | 0.83 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11115640 | 0.83 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3440754 | 0.83 | MAPT (0.74) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11159262 | 0.81 | MAPT (0.71) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590575-B | Dye intermediate N-ethyl-N-gamma-hydroxy N-propyl m-toluidine and preparation method of esterification product thereof | 绍兴君泰纺织科技有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-110590575-A | Dye intermediate N-ethyl-N-gamma-hydroxy N-propyl m-toluidine and preparation method of esterification product thereof | 绍兴君泰纺织科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-102219439-A | Chemical two component mortar composition with improved adhesion to the surface of semi-purified and/or wet bore holes in mineral base and use of same | HILTI AG | 2011-10-19 | — | — | CN | claimed |
| CN-110590575-B | Dye intermediate N-ethyl-N-gamma-hydroxy N-propyl m-toluidine and preparation method of esterification product thereof | 绍兴君泰纺织科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110590575-A | Dye intermediate N-ethyl-N-gamma-hydroxy N-propyl m-toluidine and preparation method of esterification product thereof | 绍兴君泰纺织科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| US-8044073-B2 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARMACEUTICALS (IE) | 2011-10-25 | — | — | US | disclosed |
| US-8044073-B2 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARMACEUTICALS (IE) | 2011-10-25 | — | — | US | disclosed |
| CN-102219439-A | Chemical two component mortar composition with improved adhesion to the surface of semi-purified and/or wet bore holes in mineral base and use of same | HILTI AG | 2011-10-19 | — | — | CN | disclosed |
| EP-1697343-B1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2009-07-01 | — | — | EP | disclosed |
| US-20070099924-A1 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | JANSSEN SCIENCES IRELAND UC (IE) | 2007-05-03 | — | — | US | disclosed |
| US-20070099924-A1 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | JANSSEN SCIENCES IRELAND UC (IE) | 2007-05-03 | — | — | US | disclosed |
| WO-2005058869-A1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
| EP-0297710-A1 | Disperse dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-04 | — | — | EP | disclosed |
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099924-A1 | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-2, H1-4 | MAPT 4517/4885CYP1A2 604/4885CYP3A4 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.