SCHEMBL3440754

SCHEMBL3440754

CCCCNc1cccc(C)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.74
CYP1A2 P05177 2/20 0.74
CYP3A4 P08684 1/20 0.74
CYP2D6 P10635 1/20 0.74
CYP2C9 P11712 1/20 0.74
CYP2C19 P33261 1/20 0.74
HTT P42858 1/20 0.74
F2R P25116 2/20 0.48
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ICMT O60725 1/20 0.44
GFER P55789 1/20 0.44
ALDH1A1 P00352 2/20 0.43
FBP1 P09467 1/20 0.43
TLR8 Q9NR97 1/20 0.43
TLR7 Q9NYK1 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ABL1 P00519 1/20 0.42
GAA P10253 1/20 0.42
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31519377 1.00 MAPT (0.74) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL20197373 0.94 MAPT (0.71) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL9116266 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29565935 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15231967 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5609022 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15230385 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15229858 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5597408 0.93 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL11111034 0.90 MAPT (0.83) MAPTCYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385185-B Clean preparation method of weakly alkaline arylamine azo disperse dye 大连理工大学 2017-12-05 CN claimed
JP-9056396-A None JP disclosed
WO-2025095105-A1 HYDROCRACKING CATALYST FOR CARBON-HETEROATOM BOND, METHOD FOR PRODUCING SAID HYDROCRACKING CATALYST, AND METHOD FOR HYDROCRACKING CARBON-HETEROATOM BOND エヌ・イーケムキャット株式会社 2025-05-08 WO disclosed
CN-119795709-A High-permeability composite non-woven fabric and processing technology thereof 江苏华龙无纺布有限公司 2025-04-11 CN disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
CN-105385185-B Clean preparation method of weakly alkaline arylamine azo disperse dye 大连理工大学 2017-12-05 CN disclosed
EP-1625133-B1 NITROGEN-CONTAINING MONODENTATE PHOSPHINES AND THEIR USE IN CATALYSIS EVONIK DEGUSSA GMBH (DE) 2016-06-29 EP disclosed
US-20160177371-A1 METHOD OF PRETREATMENT OF SAMPLE FOR QUANTITATING CHOLESTEROL AND METHOD FOR QUANTITATING CHOLESTEROL IN SPECIFIC LIPOPROTEINS BY USING THE SAME SEKISUI MEDICAL CO., LTD. (JP) 2016-06-23 US disclosed
CN-103176357-B Color composition for color filter and colour filter TOYO INK SC HOLDINGS CO., LTD. (JP) 2016-06-01 CN disclosed
US-9102614-B2 Naphth-2-ylacetic acid derivatives to treat AIDS GILEAD SCIENCES, INC. (US) 2015-08-11 US disclosed
US-4192841-A CONTACTING AN AQUEOUS DISPERSION OF PIGMENT WITH AN ANILINE, ACIDIFICATION CIBA-GEIGY CORPORATION (US) 1980-03-11 US disclosed
US-4189427-A Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
US-4172944-A Water insoluble styryl dyestuffs having hetero-aryl methylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-10-30 US disclosed
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed
US-4119622-A Pyrazolonylazoaniline or aminonaphtyl compounds for copying processes BASF AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-4046771-A GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4016191-A WATER INSOLUBLE; LIGHTFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
JP-H00956396-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents PNMT, NCL, NPM1 MAPT 1551/4885CYP1A2 2396/4885CYP3A4 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.