SCHEMBL11111265

SCHEMBL11111265

COCCOc1ccc(N)cc1S(=O)(=O)O.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.45
RAPGEF4 Q8WZA2 1/20 0.40
KDM4E B2RXH2 5/20 0.40
MAPT P10636 5/20 0.40
GAA P10253 4/20 0.40
ALDH1A1 P00352 4/20 0.40
POLB P06746 3/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
RECQL P46063 2/20 0.40
CASP6 P55212 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ELAVL1 Q15717 1/20 0.40
HTT P42858 2/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10788421 0.98 HSD17B10 (0.46) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL9251691 0.86 HSD17B10 (0.49) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL1606275 0.85 MAPT (0.57) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL10436156 0.85 PKM (0.42) HSD17B10KDM4EMAPTGAAALDH1A1
SCHEMBL11284193 0.84 HSD17B10 (0.50) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL156095 0.84 HSD17B10 (0.49) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL8164591 0.83 HSD17B10 (0.45) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL9812902 0.83 HSD17B10 (0.45) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL11284689 0.83 KDM4E (0.48) HSD17B10RAPGEF4KDM4EMAPTGAA
SCHEMBL10499442 0.82 HTR2C (0.46) KDM4EMAPTALDH1A1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4463079-A Heat developable color photographic materials with redox dye releasers FUJI PHOTO FILM CO., LTD. (JP) 1984-07-31 US disclosed
US-4336322-A DYE RELEASING REDOX COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-22 US disclosed
US-4268624-A Photographic light-sensitive sheet for the color diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1981-05-19 US disclosed
US-4245028-A CONTAINING AN AZO DYE RELEASING REDOX COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-01-13 US disclosed