Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404283 | 0.84 | LMNA (0.40) | MTNR1AMTNR1BLMNASLC6A4CYP1A2 | |
| SCHEMBL12450275 | 0.82 | LMNA (0.47) | MTNR1AMTNR1BLMNAMAOAPTGS1 | |
| SCHEMBL11663263 | 0.79 | LMNA (0.41) | MTNR1AMTNR1BLMNAMAOACYP1A2 | |
| SCHEMBL11911977 | 0.74 | ATM (0.40) | MTNR1AMTNR1BLMNASLC6A4MAOA | |
| SCHEMBL14463423 | 0.74 | ATM (0.40) | MTNR1AMTNR1BLMNASLC6A4MAOA | |
| SCHEMBL8718949 | 0.74 | ATM (0.40) | MTNR1AMTNR1BLMNASLC6A4MAOA | |
| SCHEMBL11022205 | 0.74 | KDM4E (0.40) | MTNR1AMTNR1BLMNASLC6A4MAOA | |
| SCHEMBL28097868 | 0.72 | LMNA (0.42) | MTNR1AMTNR1BLMNACYP1A2GAA | |
| SCHEMBL25825906 | 0.72 | LMNA (0.42) | MTNR1AMTNR1BLMNASLC6A4MAOA | |
| SCHEMBL82057 | 0.70 | MTNR1A (0.45) | MTNR1AMTNR1BLMNACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456616-A | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-06-26 | — | — | US | disclosed |