Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.43 |
| ▸ | CASR | P41180 | 10/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRK3 | P35626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10890839 | 0.99 | HTR1A (0.44) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10895740 | 0.89 | HTR1A (0.45) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10893347 | 0.82 | HTR1A (0.46) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10897446 | 0.80 | HTR1A (0.42) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL10890896 | 0.79 | SLC2A1 (0.45) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| SCHEMBL11743303 | 0.79 | HTR1A (0.57) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| Hydrochloric Acid SCHEMBL10889455 | 0.78 | SLC2A1 (0.44) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| Hydrochloric Acid SCHEMBL10892320 | 0.77 | ACHE (0.45) | CYP2D6ADRB2MEN1KMT2AL3MBTL1 | |
| SCHEMBL10893417 | 0.76 | HTR1A (0.61) | HTR1AADRA2AADRA2BMAOAHTR2B | |
| Hydrochloric Acid SCHEMBL10891439 | 0.76 | HTR1A (0.60) | HTR1AADRA2AADRA2BMAOAHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097202-A1 | Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1984-01-04 | — | — | EP | disclosed |