Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970323 | 0.82 | NFE2L2 (0.59) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL30333699 | 0.81 | NFE2L2 (0.49) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL4685419 | 0.81 | NFE2L2 (0.49) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL8993328 | 0.81 | NFE2L2 (0.49) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL1515311 | 0.79 | NFE2L2 (0.47) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL4685420 | 0.79 | NFE2L2 (0.47) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL14532278 | 0.79 | NFE2L2 (0.47) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL26694715 | 0.79 | NFE2L2 (0.47) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL4683019 | 0.78 | NFE2L2 (0.58) | KDM4EPKMNFE2L2KEAP1L3MBTL1 | |
| SCHEMBL6419585 | 0.76 | NFE2L2 (0.45) | KDM4EPKMNFE2L2KEAP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103660-A1 | Pyridine-1-oxides, herbicidal compositions thereof and herbicidal methods for applying the compounds | UNIROYAL, INC. (US) | 1984-03-28 | — | — | EP | disclosed |
| US-4360677-A | Herbicidal 2-(alpha-chloromethylsulfonyl) pyridine-1-oxides | UNIROYAL, INC. (US) | 1982-11-23 | — | — | US | disclosed |