Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30333699 | 1.00 | NFE2L2 (0.49) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL20570398 | 0.86 | NFE2L2 (0.53) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL28483882 | 0.83 | NPC1 (0.40) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL14426916 | 0.83 | KEAP1 (0.57) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL4685419 | 0.83 | NFE2L2 (0.49) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL28486998 | 0.82 | NFE2L2 (0.38) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL28491554 | 0.82 | NFE2L2 (0.38) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL29866356 | 0.81 | NPC1 (0.43) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| Sulfuric Acid SCHEMBL29282608 | 0.81 | KEAP1 (0.49) | NFE2L2KEAP1L3MBTL1KDM4EPKM | |
| SCHEMBL3413877 | 0.81 | KEAP1 (0.60) | NFE2L2KEAP1L3MBTL1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062759-B | Ethylsulfonyl-containing pyridine-1, 2, 4-oxadiazole substituted benzamide compounds and preparation method and application thereof | 浙江工业大学 | 2021-11-23 | — | — | CN | claimed |
| CN-112062759-A | Ethylsulfonyl-containing pyridine-1, 2, 4-oxadiazole substituted benzamide compounds and preparation method and application thereof | 浙江工业大学 | 2020-12-11 | — | — | CN | claimed |
| CN-120192272-A | Preparation method of benzoxazole intermediate | 帕潘纳(北京)科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-119184103-A | Active pesticide for preventing and controlling fruit fly of carambola | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | 2024-12-27 | — | — | CN | disclosed |
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116602298-B | Pharmaceutical composition and application thereof | 上海泰禾化工有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-11814348-B2 | Oxidizing liquid media for chemical transformations | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230286968-A1 | ARYLOXAZOLO SPIRAL RING DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2023-08-31 | — | — | US | disclosed |
| CN-116602298-A | Pharmaceutical composition and application thereof | 上海泰禾化工有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-11396492-B2 | Direct oxidative amination of hydrocarbons | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-07-26 | — | — | US | disclosed |
| WO-2008106224-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008106226-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008106225-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| CN-1926127-A | Novel 2-heteroaryl substituted benzimidazole derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-07 | — | — | CN | disclosed |
| WO-2007025284-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | disclosed |
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | NFE2L2 1841/4885KEAP1 1957/4885L3MBTL1 4113/4885 |
| US-20230272002-A1 | PHOTOREDOX PROTEIN MODIFICATION | PPOX, CACYBP, BRI3BP | NFE2L2 1060/4885KEAP1 903/4885L3MBTL1 2997/4885 |
| US-11396492-B2 | Direct oxidative amination of hydrocarbons | GPX4, AOC2, NOX1 | NFE2L2 20/4885KEAP1 40/4885L3MBTL1 2539/4885 |
| US-11814348-B2 | Oxidizing liquid media for chemical transformations | HAO2, LPO, DUOX1 | NFE2L2 204/4885KEAP1 672/4885L3MBTL1 4547/4885 |
| US-20230286968-A1 | ARYLOXAZOLO SPIRAL RING DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, CYP4B1, CYP1B1 | NFE2L2 285/4885KEAP1 449/4885L3MBTL1 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.