Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329100 | 0.83 | CYP2D6 (0.47) | CHRM2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL16983643 | 0.82 | MEN1 (0.49) | CHRM2LTA4HTSHRMEN1KMT2A | |
| SCHEMBL1110765 | 0.78 | CYP1A2 (0.39) | CHRM2LTA4HTSHRMEN1KMT2A | |
| SCHEMBL16983706 | 0.78 | PRMT1 (0.51) | CHRM2 | |
| SCHEMBL10991195 | 0.77 | CHRM2 (0.48) | CHRM2KMT2AMAOBBCHEACHE | |
| SCHEMBL3475302 | 0.77 | CHRM2 (0.48) | CHRM2KMT2AMAOBBCHEACHE | |
| SCHEMBL14948896 | 0.77 | CHRM2 (0.46) | CHRM2LTA4HTSHRMEN1KMT2A | |
| SCHEMBL13347694 | 0.77 | CHRM2 (0.46) | CHRM2LTA4HTSHRMEN1KMT2A | |
| SCHEMBL4602387 | 0.76 | ALDH1A1 (0.38) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9615556 | 0.76 | SLC6A4 (0.40) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280033-B1 | DICYCLOPENTADIENE METATHESIS POLYMERISATION CATALYST | LTD LIABILITY COMPANY UNITED RES AND DEV CT (RU) | 2014-03-12 | — | — | EP | disclosed |
| EP-2280033-A1 | DICYCLOPENTADIENE METATHESIS POLYMERISATION CATALYST | Limited Liability Company "United Research and Development Centre" (RU) | 2011-02-02 | — | — | EP | disclosed |