SCHEMBL4602387

SCHEMBL4602387

C=Cc1ccccc1CCOC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.35
KDM4E B2RXH2 3/20 0.33
MITF O75030 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GSK3B P49841 1/20 0.31
CA2 P00918 1/20 0.31
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HPGD P15428 1/20 0.31
MAP2K7 O14733 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2404989 0.84 ALDH1A1 (0.40) ALDH1A1TSHRMITFHTTSMN1; SMN2
SCHEMBL16537542 0.81 ALDH1A1 (0.32) ALDH1A1
SCHEMBL595200 0.81 ALDH1A1 (0.48) ALDH1A1TSHRMITFTAAR1MAPT
SCHEMBL29377653 0.81 ALDH1A1 (0.48) ALDH1A1TSHRMITFTAAR1MAPT
SCHEMBL296248 0.81 ALDH1A1 (0.38) ALDH1A1MITFHTTSMN1; SMN2HPGD
SCHEMBL1200782 0.81 ALDH1A1 (0.47) ALDH1A1TSHRMEN1KMT2ACA2
SCHEMBL58238 0.80 ALDH1A1 (0.40) ALDH1A1TSHRKDM4EMAPTMEN1
SCHEMBL31602197 0.80 ALDH1A1 (0.40) ALDH1A1TSHRKDM4EMAPTMEN1
SCHEMBL13784839 0.80 SLC6A2 (0.33) ALDH1A1TSHRKDM4EMAPTMEN1
SCHEMBL16538048 0.80 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed