Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111572 | 1.00 | MAOB (0.38) | MAOBTLR4CYP3A4MAPK1NPSR1 | |
| SCHEMBL6668121 | 0.82 | ALOX12 (0.42) | TLR4CYP3A4MAPK1NPSR1PPP1R15A | |
| SCHEMBL3697881 | 0.76 | GAA (0.44) | MAOBNPSR1PPP1R15AMELKPPP1R15B | |
| SCHEMBL658824 | 0.72 | ERN1 (0.47) | CYP3A4MAPK1NPSR1L3MBTL1TSHR | |
| SCHEMBL28420537 | 0.72 | POLB (0.56) | TLR4MAPK1L3MBTL1HPGDKMT2A | |
| SCHEMBL2319124 | 0.72 | POLB (0.56) | TLR4MAPK1L3MBTL1HPGDKMT2A | |
| SCHEMBL30275282 | 0.71 | L3MBTL1 (0.59) | MAOBNPSR1PPP1R15AMELKPPP1R15B | |
| SCHEMBL6847216 | 0.71 | L3MBTL1 (0.59) | MAOBNPSR1PPP1R15AMELKPPP1R15B | |
| SCHEMBL2697239 | 0.68 | ERN1 (0.57) | CYP3A4NPSR1L3MBTL1TSHRHPGD | |
| SCHEMBL30301104 | 0.68 | MAOB (0.47) | MAOBCYP3A4MAPK1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474952-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |