Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111693 | 1.00 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1POLB | |
| SCHEMBL8773436 | 0.78 | CYP1A2 (0.43) | TSHRALDH1A1POLBAKT1CYP1A2 | |
| SCHEMBL10862635 | 0.78 | CES2 (0.41) | ALDH1A1TDP1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10862631 | 0.78 | CES2 (0.41) | ALDH1A1TDP1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9562364 | 0.73 | CES2 (0.41) | TSHRALDH1A1MAPK1POLBAKT1 | |
| SCHEMBL9562359 | 0.73 | CES2 (0.41) | TSHRALDH1A1MAPK1POLBAKT1 | |
| SCHEMBL10439102 | 0.72 | POLB (0.64) | TSHRALDH1A1MAPK1TDP1POLB | |
| SCHEMBL1796055 | 0.72 | POLB (0.64) | TSHRALDH1A1MAPK1TDP1POLB | |
| SCHEMBL1796053 | 0.72 | POLB (0.64) | TSHRALDH1A1MAPK1TDP1POLB | |
| SCHEMBL27607916 | 0.70 | TDP1 (0.39) | TSHRALDH1A1MAPK1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465630-A | Tetraazaannulene cobalt complex compounds and method for preparation therefor | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | disclosed |
| EP-0073456-A1 | Tetraazaannulene cobalt complex compounds and method for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-03-09 | — | — | EP | disclosed |