Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562359 | 1.00 | CES2 (0.41) | CES2CES1KMT2AKDM4EMEN1 | |
| SCHEMBL7552512 | 0.84 | TDP1 (0.41) | KMT2AKDM4EMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7552509 | 0.84 | TDP1 (0.41) | KMT2AKDM4EMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10784885 | 0.78 | ALDH1A1 (0.37) | KMT2AKDM4EMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5487477 | 0.76 | CES2 (0.46) | CES2CES1SMN1; SMN2EGFRAKT1 | |
| SCHEMBL8773436 | 0.75 | CYP1A2 (0.43) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL4291901 | 0.74 | RAB9A (0.48) | CES2CES1KMT2AKDM4EMEN1 | |
| SCHEMBL4291907 | 0.74 | RAB9A (0.48) | CES2CES1KMT2AKDM4EMEN1 | |
| SCHEMBL11111693 | 0.73 | TSHR (0.38) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL11111689 | 0.73 | TSHR (0.38) | KMT2AKDM4EMEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182401-A | Bactericide intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-26 | — | — | US | disclosed |