Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113541 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1CHRM3CHRNA7MEN1 | |
| SCHEMBL11109479 | 0.83 | CHRNA7 (0.41) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11115518 | 0.81 | CHRM2 (0.36) | CHRM2CHRM1CHRM3CHRNA7ALDH1A1 | |
| SCHEMBL11117209 | 0.81 | HTR3A (0.41) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11128579 | 0.81 | CHRM3 (0.42) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11113361 | 0.80 | CHRNA7 (0.44) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11116121 | 0.80 | CHRM3 (0.38) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11115203 | 0.80 | CHRM2 (0.39) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11115200 | 0.77 | CHRNA7 (0.38) | CHRM2CHRM1CHRM3CHRNA7HTR3A | |
| SCHEMBL11000923 | 0.77 | CHRM2 (0.43) | CHRM2CHRM1CHRM3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |
| EP-0038564-A1 | Dibenz (b,e) oxepin derivatives and pharmaceutical compositions comprising them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1981-10-28 | — | — | EP | disclosed |