Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569746 | 0.77 | TNKS (0.31) | PDE4BPDE4D | |
| SCHEMBL11104756 | 0.77 | PDE4B (0.36) | PDE4BPDE4D | |
| SCHEMBL7389179 | 0.77 | TNKS (0.33) | PDE4BPDE4D | |
| SCHEMBL12209146 | 0.75 | PDE4B (0.32) | PDE4BPDE4D | |
| SCHEMBL31571895 | 0.75 | PDE4B (0.38) | PDE4BPDE4D | |
| SCHEMBL30678844 | 0.73 | PDE4B (0.34) | PDE4BPDE4D | |
| SCHEMBL29277041 | 0.73 | PDE4B (0.34) | PDE4BPDE4D | |
| SCHEMBL21099276 | 0.72 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL11290218 | 0.72 | HTT (0.45) | YTHDC1XDHPDE2A | |
| SCHEMBL6457209 | 0.72 | HTT (0.48) | YTHDC1XDHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435566-A | HYPOGLYCEMIA, ANTIHISTAMINE, ANTIDIABETIC ACTIVITY | MARUKO SEIYAKU CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |