Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187242 | 0.92 | — | — | |
| SCHEMBL29277041 | 0.76 | PDE4B (0.34) | PDE4BPDE4D | |
| SCHEMBL30678844 | 0.76 | PDE4B (0.34) | PDE4BPDE4D | |
| SCHEMBL11112029 | 0.75 | PDE4B (0.35) | PDE4BPDE4D | |
| SCHEMBL373579 | 0.70 | — | — | |
| SCHEMBL11104756 | 0.69 | PDE4B (0.36) | PDE4BPDE4D | |
| SCHEMBL31622413 | 0.69 | — | — | |
| SCHEMBL14734141 | 0.69 | LATS1 (0.33) | — | |
| SCHEMBL30639334 | 0.69 | LATS1 (0.33) | — | |
| SCHEMBL373964 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380891-A1 | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |