Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106307 | 0.81 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL11103684 | 0.81 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| Hydrochloric Acid SCHEMBL11113853 | 0.80 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL11111082 | 0.79 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL11108975 | 0.78 | NR3C1 (0.54) | NR3C1 | |
| SCHEMBL11105960 | 0.78 | NR3C1 (0.39) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL11104375 | 0.77 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL11107045 | 0.76 | MTNR1A (0.38) | ALDH1A1TDP1MAPTTSHRKMT2A | |
| SCHEMBL11110128 | 0.76 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL11104429 | 0.74 | KDM4E (0.45) | KDM4EHSD17B10ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |