Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107901 | 0.80 | KDM4E (0.42) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL11110017 | 0.76 | ALDH1A1 (0.63) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL9444308 | 0.75 | PSMB5 (0.49) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL9444249 | 0.75 | ALDH1A1 (0.61) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL4508936 | 0.73 | ALDH1A1 (0.63) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL11113740 | 0.73 | KDM4E (0.46) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL4481625 | 0.71 | KDM4E (0.37) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL9444373 | 0.70 | MEN1 (0.49) | KDM4EHTTATMALDH1A1HPGD | |
| SCHEMBL4508215 | 0.69 | ALDH1A1 (0.67) | KDM4EHTTALDH1A1HPGDMAPT | |
| SCHEMBL20480150 | 0.69 | KDM4E (0.47) | KDM4EHTTATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |