Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620525 | 0.75 | KDM4E (0.42) | KDM4EHTTATMCNR1CNR2 | |
| SCHEMBL11110017 | 0.75 | ALDH1A1 (0.63) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL11111608 | 0.75 | KDM4E (0.68) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL9444249 | 0.74 | ALDH1A1 (0.61) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL9444261 | 0.74 | KDM4E (0.69) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL9444308 | 0.74 | PSMB5 (0.49) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL15545297 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTAKT1 | |
| SCHEMBL11112232 | 0.73 | KDM4E (0.40) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL11107901 | 0.72 | KDM4E (0.42) | KDM4EHTTATMKMT2AALDH1A1 | |
| SCHEMBL4508936 | 0.72 | ALDH1A1 (0.63) | KDM4EHTTATMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |